Synthesis of ( E )-vinyl sulfides via copper-catalyzed hydrothiolation of internal alkynes with thiosulfonates and silanes

A copper-catalyzed syn -hydrothiolation of internal alkynes with thiosulfonates and silanes has been disclosed, which offers regio- and stereoselective access to ( E )-vinyl sulfides. This highly selective process, which can be performed on a gram-scale, features operational simplicity and conditions not involving the use of smelly thiols.