"Fruit in a tooth" - A rare non - Syndromic anomaly - 2 rare case reports with a genetic analysis

Tooth agenesis is one of the most common developmental anomalies affecting function and aesthetics. Genetic mutations cause non-syndromic tooth agenesis and involve the interaction of genes of tooth epithelium and mesenchyme odontogenesis. This article is the first in the literature to present non-s...

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Veröffentlicht in:Journal of Indian Academy of Oral Medicine and Radiology 2022-10, Vol.34 (4), p.484-487
Hauptverfasser: Murugan, Arul, Anuradha, G, Kannan, A, Lakshmi, Krithika
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Sprache:eng
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Zusammenfassung:Tooth agenesis is one of the most common developmental anomalies affecting function and aesthetics. Genetic mutations cause non-syndromic tooth agenesis and involve the interaction of genes of tooth epithelium and mesenchyme odontogenesis. This article is the first in the literature to present non-syndromic cases of two siblings reported with mulberry molars, morphological changes in teeth (hypodontia and microdontia), and a genetic study performed to substantiate the involvement of Paired box gene 9 in tooth agenesis and morphogenesis.
ISSN:0972-1363
0975-1572
DOI:10.4103/jiaomr.jiaomr_84_22