Preparation and characterization of novel nanofibrous composites prepared by electrospinning as potential nerve guidance conduits (NGCs)

[...]biomaterials were confirmed to be non-cytotoxic to L929 mouse fibroblasts and 1321N1 human glial cells. [...]generation nerve cords are porous, biodegradable tubes made of well-studied, biocompatible materials such as polyglycolic acid (PGA) and poly-DL-lactide-co-caprolactone (PLCL), type I collagen or fibroin [4]. [...]of applying an electric voltage in the polymer solution, electric charges are generated. [...]they have similar structural features and functions to the extracellular matrix (ECM) [10, 11]. [...]the addition of the right type of nanoparticles in tissue engineering can significantly improve the biological, mechanical, and electrical properties of the scaffolds and can also provide various functions depending on the applications [8].