Immunostimulatory and Anti-Aging Effects of Sericin Powders Extracted from Antheraea yamamai

Immunostimulatory and Anti-Aging Effects of Sericin Powders Extracted from Antheraea yamamai

We investigated the effect of sericin powder extracted from cocoons of the mulberry silkworm, Bombyx mori, and the non-mulberry silkworm, Antheraea yamamai, on lymphocyte proliferation. Sericin from A. yamamai (AS) elicited significant proliferation of B-lymphocytes. B. mori sericin (BS) and AS exte...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of Insect Biotechnology and Sericology 2023, Vol.92(3), pp.3_055-3_064
Hauptverfasser: Karimazawa, Mayumi, Adachi, Takahiro, Sillapakong, Piyamas, Yamashita, Tetsuro
Format: Artikel
Sprache:eng
Schlagworte:
Antheraea yamamai
Bombyx mori
CD69 antigen
CD86 antigen
Cytokines
Immunostimulation
Life span
lifespan
Lymphocytes
Lymphocytes B
sericin
Silkworms
transcriptome analysis
Transcriptomes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We investigated the effect of sericin powder extracted from cocoons of the mulberry silkworm, Bombyx mori, and the non-mulberry silkworm, Antheraea yamamai, on lymphocyte proliferation. Sericin from A. yamamai (AS) elicited significant proliferation of B-lymphocytes. B. mori sericin (BS) and AS extended the lifespan of Caenorhabditis elegans. Transcriptome analysis revealed that AS increased the expression of CD86 and CD69, along with the proinflammatory cytokine IL-1βand the regulatory cytokine IL-10, in mouse spleen cells. The immunostimulatory effect of AS suggests that it has therapeutic value.
ISSN:1346-8073
1884-7978
DOI:10.11416/jibs.92.3_055