Electroencephalogram and Neuroimaging (MRI) Findings in First Episode of Unprovoked Seizures in Children

BACKGROUND FUS (First Unprovoked Seizure) is defined as the first seizure that is not feverish and that cannot be attributed to an immediate, clear-cut cause, such as an intracranial infection or head injury. Improvements in diagnostic techniques have increased the chances of finding the unknown causes.The most crucial investigative instrument for the diagnosis and treatment of epilepsies is the EEG. Specific epilepsy disorders can be diagnosed with EEG because it can identify focal lesions that are invisible with neuroimaging and have epileptiform signs. Unlike the recommendations for adult patients undergoing neuroimaging, there is not enough data to establish a standard recommendation or guideline for regular neuroimaging for children experiencing their FUS. This study was conducted to delve into the role of neuroimaging (MRI) and EEG combined in the first episode of unprovoked seizures and to establish a correlation, if any, between EEG and MRI findings as well as between clinical features and abnormal EEG and MRI findings. MATERIALS AND METHODS This was a prospective descriptive observational study involving 50 children belonging to the age group of 3 months to 18 years admitted with their first episode of seizures. EEG recordings and findings of MRI scans were recorded and the data was analyzed using the SPSS version 21.0 software. Continuous variables were presented as mean+/-SD. Categorical variables were expressed as frequencies and percentages. The Fisher’s exact test was used to determine if there is a relationship between two variables. P