Does Vinblastine Retain its Anticancer Effect in the Presence of Cyclodextrin? A Preliminary Study

Does Vinblastine Retain its Anticancer Effect in the Presence of Cyclodextrin? A Preliminary Study

Vinblastine was investigated in the presence of cyclodextrin derivatives on different cancer cells and it was established that the anticancer activity was unchanged. This was the first step of a long procedure resulting in the dosage of vinblastine together with cyclodextrin or its derivatives to im...

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Veröffentlicht in:Periodica polytechnica. Chemical engineering. 2024-01, Vol.68 (2), p.133
Hauptverfasser: Keglevich, Péter, Zupkó, István, Szente, Lajos, Puskás, István, Szigetvári, Áron, Mayer, Szabolcs, Hazai, László
Format: Artikel
Sprache:eng
Schlagworte:
Anticancer properties
Cancer
Chemical bonds
Chemical engineering
Cyclodextrins
R&D
Research & development
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Zusammenfassung:Vinblastine was investigated in the presence of cyclodextrin derivatives on different cancer cells and it was established that the anticancer activity was unchanged. This was the first step of a long procedure resulting in the dosage of vinblastine together with cyclodextrin or its derivatives to improve the adverse effects.
ISSN:0324-5853
1587-3765
DOI:10.3311/PPch.23503