A New Prenylated Hydroquinone from the Fruiting Bodies of Ganoderma calidophilum

Prenylated hydroquinones are the main meroterpenoids found in fungal species of the genus Ganoderma. A new prenylated hydroquinone ganocalidin G ( 1 ) was isolated from the fruiting bodies of Ganoderma calidophilum . The structure of compound 1 was identified based on 1D and 2D NMR spectroscopy as w...

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Veröffentlicht in:Chemistry of natural compounds 2024, Vol.60 (3), p.403-406
Hauptverfasser: Ma, Qing-Yun, Zhang, Ting-Ting, Yang, Li, Xie, Qing-Yi, Dai, Hao-Fu, Yu, Zhi-Fang, Zhao, You-Xing
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Sprache:eng
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Zusammenfassung:Prenylated hydroquinones are the main meroterpenoids found in fungal species of the genus Ganoderma. A new prenylated hydroquinone ganocalidin G ( 1 ) was isolated from the fruiting bodies of Ganoderma calidophilum . The structure of compound 1 was identified based on 1D and 2D NMR spectroscopy as well as MS. Its absolute structure was elucidated from optical rotation calculation. The bioassay for inhibitory activity against AChE showed compound 1 had weak activity with an inhibition rate of 28.7% at a concentration of 100 μM.
ISSN:0009-3130
1573-8388
DOI:10.1007/s10600-024-04337-z