Nanodispersions for drug delivery applications: a special focus toward cancer therapeutics

Nanotechnology has expanded in drug delivery applications in recent years due to inherent features such as drug compatibility, improved solubility/bioavailability of poorly soluble drugs. Nanotechnology based drug delivery system offers multiple benefits such as site specific and targeted delivery....

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Veröffentlicht in:Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology 2024-06, Vol.26 (6), p.116, Article 116
Hauptverfasser: Sethuraman, Vaidevi, Ramesh, Abilesh, Janakiraman, Kumar, Balakrishnan, Nagaraj
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Sprache:eng
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Zusammenfassung:Nanotechnology has expanded in drug delivery applications in recent years due to inherent features such as drug compatibility, improved solubility/bioavailability of poorly soluble drugs. Nanotechnology based drug delivery system offers multiple benefits such as site specific and targeted delivery. Nanodispersions are nanoparticle-containing dispersed systems that resolve the shortcomings associated with conventional drug delivery strategies. Nanodispersion are submicron size particles with drug and stabilized with surfactants and categorized as nanosuspension, nanoemulsions, cubosomes, etc. Nanodispersion has showed effective drug delivery to the targeted site, effective in killing cancerous cells without harming normal cells, reduces toxicity, and protects drug from environment. These properties of nanodispersion made it to be effective delivery system. In this review, we have focused on the overview of nanodispersion preparation techniques as well as potential innovations in drug delivery and cancer therapeutics. Furthermore, we have added information on the recent developments and perspectives in nanomedicine and drug delivery. Graphical Abstract
ISSN:1388-0764
1572-896X
DOI:10.1007/s11051-024-06026-y