Analysis of clinical manifestations and prognostic factors of herpes simplex virus type 1 encephalitis

ObjectiveTo analyze the clinical features and prognostic factors of herpes simplex virus type 1 (HSV‐1) encephalitis. MethodsA total of 51 patients with HSV‐1 encephalitis hospitalized in He'nan Provincial People's Hospital from January 2018 to September 2023 were selected, and their clini...

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Veröffentlicht in:Zhongguo xian dai shen jing ji bing za zhi 2024-01, Vol.24 (4), p.224
Hauptverfasser: Kun‐rong XU, Xiao‐juan WANG, Mi‐lan ZHANG, Hong‐fei XUE, Jia‐jia XU, LI, Wei
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container_start_page 224
container_title Zhongguo xian dai shen jing ji bing za zhi
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creator Kun‐rong XU
Xiao‐juan WANG
Mi‐lan ZHANG
Hong‐fei XUE
Jia‐jia XU
LI, Wei
description ObjectiveTo analyze the clinical features and prognostic factors of herpes simplex virus type 1 (HSV‐1) encephalitis. MethodsA total of 51 patients with HSV‐1 encephalitis hospitalized in He'nan Provincial People's Hospital from January 2018 to September 2023 were selected, and their clinical data, laboratory and imaging examination results were recorded. The modified Rankin Scale (mRS) was used to evaluate the prognosis of patients and the recovery of neurological function after brain injury. Univariate and multivariate stepwise Logistic regression analyses were screened for risk factors of adverse prognosis of HSV‐1 encephalitis. ResultsThe main symptoms of 51 cases were fever and headache. The serological examination results showed increased white blood cell count (14 cases), increased neutrophil count (14 cases), decreased lymphocyte count (8 cases), and decreased serum sodium level (17 cases). Cerebrospinal fluid (CSF) examination by lumbar puncture showed increased CSF pressure (18 cases), increased whi
doi_str_mv 10.3969/j.issn.1672‐6731.2024.04.005
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MethodsA total of 51 patients with HSV‐1 encephalitis hospitalized in He'nan Provincial People's Hospital from January 2018 to September 2023 were selected, and their clinical data, laboratory and imaging examination results were recorded. The modified Rankin Scale (mRS) was used to evaluate the prognosis of patients and the recovery of neurological function after brain injury. Univariate and multivariate stepwise Logistic regression analyses were screened for risk factors of adverse prognosis of HSV‐1 encephalitis. ResultsThe main symptoms of 51 cases were fever and headache. The serological examination results showed increased white blood cell count (14 cases), increased neutrophil count (14 cases), decreased lymphocyte count (8 cases), and decreased serum sodium level (17 cases). Cerebrospinal fluid (CSF) examination by lumbar puncture showed increased CSF pressure (18 cases), increased whi</description><identifier>ISSN: 1672-6731</identifier><identifier>DOI: 10.3969/j.issn.1672‐6731.2024.04.005</identifier><language>chi</language><publisher>Tianjin Shi: Tianjin Huanhu Hospital</publisher><subject>Encephalitis ; Glucose ; Herpes viruses ; Leukocytes ; Medical prognosis ; Regression analysis ; Risk factors</subject><ispartof>Zhongguo xian dai shen jing ji bing za zhi, 2024-01, Vol.24 (4), p.224</ispartof><rights>2024. This work is published under http://creativecommons.org/licenses/by/3.0/ (the “License”). 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subjects Encephalitis
Glucose
Herpes viruses
Leukocytes
Medical prognosis
Regression analysis
Risk factors
title Analysis of clinical manifestations and prognostic factors of herpes simplex virus type 1 encephalitis
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