Potential of [99mTc] Tc-IONPs in SPECT: a systematic review on efficiency and accumulation rates

Potential of [99mTc] Tc-IONPs in SPECT: a systematic review on efficiency and accumulation rates

The aim of this study is to compare the efficiency and accumulation of 99m Tc attached to iron oxide nanoparticles (IONPs) for use in the SPECT imaging. A comprehensive literature search identified 13 relevant studies, and the maximum absorbed dose per gram (ID/g) of [ 99m Tc ] Tc -IONPs in various...

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Veröffentlicht in:Journal of radioanalytical and nuclear chemistry 2024-05, Vol.333 (5), p.2231-2250
Hauptverfasser: Garshad, Javad, Salarvand, Ali, Tavakoli, Morteza, Mansourian, Mahsa
Format: Artikel
Sprache:eng
Schlagworte:
Accumulation
Chemistry
Chemistry and Materials Science
Diagnostic Radiology
Hadrons
Heavy Ions
Imaging
Inorganic Chemistry
Iron oxides
Nanoparticles
Nuclear Chemistry
Nuclear Physics
Physical Chemistry
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Zusammenfassung:The aim of this study is to compare the efficiency and accumulation of 99m Tc attached to iron oxide nanoparticles (IONPs) for use in the SPECT imaging. A comprehensive literature search identified 13 relevant studies, and the maximum absorbed dose per gram (ID/g) of [ 99m Tc ] Tc -IONPs in various organs at different time intervals was analyzed. The findings showed the distribution patterns of the compounds in each organ, emphasizing the significance of coating and nanoparticle size for optimal imaging results. By selecting the appropriate coating and nanoparticle size, imaging quality and accuracy can be improved.
ISSN:0236-5731
1588-2780
DOI:10.1007/s10967-024-09480-z