Cover Feature: Biocatalytic and Regioselective Exchange of 2‐O‐Benzoyl for 2‐O‐(m‐Substituted)Benzoyl Groups to Make Precursors of Next‐Generation Paclitaxel Drugs (ChemCatChem 9/2024)

The Cover Feature illustrates the application of a benzoyltransferase catalyzing the debenzoylation of taxane precursors used to make old‐generation paclitaxel compounds, followed by the rearoylation of the precursors destined for making new‐generation paclitaxel compounds used to treat drug‐resista...

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Veröffentlicht in:ChemCatChem 2024-05, Vol.16 (9), p.n/a
Hauptverfasser: Al‐Hilfi, Aimen, Li, Zhen, Merz, Kenneth M., Nawarathne, Irosha N., Walker, Kevin D.
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Sprache:eng
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Zusammenfassung:The Cover Feature illustrates the application of a benzoyltransferase catalyzing the debenzoylation of taxane precursors used to make old‐generation paclitaxel compounds, followed by the rearoylation of the precursors destined for making new‐generation paclitaxel compounds used to treat drug‐resistant cancer cells. More information can be found in the Research Article by I. N. Nawarathne, K. D. Walker et al.
ISSN:1867-3880
1867-3899
DOI:10.1002/cctc.202480903