SERS-Based Rapid Detection of Botulinum Toxin A Using an Aptasensor

SERS-Based Rapid Detection of Botulinum Toxin A Using an Aptasensor

A biosensor for the rapid and sensitive detection of botulinum toxin type A was developed. The sensor is a SERS substrate with an optimized concentration of labeled aptamers immobilized on its surface. It allows the detection of botulinum toxin type A with a detection limit of 2.4 ng/mL in 1 h.

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Veröffentlicht in:Bulletin of the Russian Academy of Sciences. Physics 2024-02, Vol.88 (2), p.193-198
Hauptverfasser: Ambartsumyan, O. A., Brovko, A. M.
Format: Artikel
Sprache:eng
Schlagworte:
Biosensors
Hadrons
Heavy Ions
Nuclear Physics
Physics
Physics and Astronomy
Substrates
Toxins
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Zusammenfassung:A biosensor for the rapid and sensitive detection of botulinum toxin type A was developed. The sensor is a SERS substrate with an optimized concentration of labeled aptamers immobilized on its surface. It allows the detection of botulinum toxin type A with a detection limit of 2.4 ng/mL in 1 h.
ISSN:1062-8738
1934-9432
DOI:10.1134/S1062873823705214