Inside Cover: Stereochemistry‐Dependent Labeling of Organelles with a Near‐Infrared‐Emissive Phosphorus‐Bridged Rhodamine Dye in Live‐Cell Imaging (Angew. Chem. Int. Ed. 15/2024)

Inside Cover: Stereochemistry‐Dependent Labeling of Organelles with a Near‐Infrared‐Emissive Phosphorus‐Bridged Rhodamine Dye in Live‐Cell Imaging (Angew. Chem. Int. Ed. 15/2024)

A photostable NIR‐emissive labeling agent is presented by Masayasu Taki, Yasushi Okada, Florence Tama, Shigehiro Yamaguchi et al. in their Research Article (e202400711). Stereoisomers of the present compounds, based on phosphorus‐bridged rhodamine, exhibit different staining abilities in live cells....

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Veröffentlicht in:Angewandte Chemie International Edition 2024-04, Vol.63 (15), p.n/a
Hauptverfasser: Wu, Qian, Taki, Masayasu, Tanaka, Yoshiki, Kesherwani, Manish, Phung, Quan Manh, Enoki, Sawako, Okada, Yasushi, Tama, Florence, Yamaguchi, Shigehiro
Format: Artikel
Sprache:eng
Schlagworte:
Isomers
Labeling
Labels
Lipid bilayers
Lipids
Organelles
Phosphorus
Rhodamine
Stereochemistry
Stereoisomerism
Stereoisomers
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Zusammenfassung:A photostable NIR‐emissive labeling agent is presented by Masayasu Taki, Yasushi Okada, Florence Tama, Shigehiro Yamaguchi et al. in their Research Article (e202400711). Stereoisomers of the present compounds, based on phosphorus‐bridged rhodamine, exhibit different staining abilities in live cells. The trans‐isomer is able to permeate organelle membranes and label target proteins, whereas the cis‐isomer accumulates nonspecially on lipid bilayers.
ISSN:1433-7851
1521-3773
DOI:10.1002/anie.202404238