Evaluation of effect of the inflammatory biomarkers on mortality in patients with acute stroke in intensive care unit

The stroke is a major public health problem due to its high prevalence worldwide, causing mortality and morbidity. The inflammatory response that begins after acute stroke is considered to be an important pathological process involving secondary injury after ischemic and hemorrhagic brain injury. In the inflammatory process; platelets also play a role in inflammation and are responsible for chemokine cytokine production. Patients with acute stroke have an important place among patients in need of intensive care. In this study, we tried to determine the effect of neutrophil / lymphocyte ratio (NLR) and platelet / lymphocyte ratio (PLR) on prognosis in patients with acute stroke 400 acute stroke patients who were hospitalized in Dicle University Hospital Internal Medicine Intensive Care Unit and Neurology Intensive Care Unit between January 2012 and November 2019 were included in this study. Acute stroke defined as ischemic and hemorrhagic stroke. The study was designed retrospectively. The demographic characteristics, etiologies, comorbid diseases and laboratory findings of patients were taken from patient files. Length of stay and clinical results in the intensive care unit were recorded. Neutrophil-lymphocyte ratio (NLR) and platelet lymphocyte ratio (PLR) were measured. Patients were classified as died (group 1) and survived (group2). Two groups were compared with the parameters studied. Group 1, n:227 and group 2 n:173. Age, length of hospitalization, systolic blood pressure, diastolic blood pressure, leukocyte count, neutrophil count, platelet count, blood glucose, creatinine, CRP, neutrophil / lymphocyte ratio (NLR), platelet / lymphocyte ratio (PLR) was found to be statistically significant in group:1 compared to the group:2. These parameters were higher in group 1 than group 2 (p