The effectiveness of bacteriophages in lysing antibiotic-resistant Escherichia coli from river in palembang city

Contamination of antibiotic-resistant Escherichia coli in the aquatic environment in Palembang City, Sumatra Selatan, Indonesia, is dangerous for human health, especially for those who use the water for hygiene and sanitation purposes, because it is a pathogenic bacterium that causes diseases. A solution is needed to solve this problem. Bacteriophage is a natural biocontrol safe for human health and can lyse its host, E. coli. In this study, isolated bacteriophages from 3 rivers in Palembang city, namely the Kedukan River, Buah River and PU River, and tested the Effectiveness of bacteriophage lysis against E. coli. This research, after isolating antibiotic-resistant E. coli from river waters in Palembang City and coding the sample with EcSK2-2, EcSK3-1, EcSB1-3, EcSB3-3, EcPU1-1, and EcPU3-1, isolated phages coded FgSK22. 3, FgSK31.1, FgSB13.1, FgSB33.2, FgSB33.3, FgPU11.1, and FgPU31.2. The isolates could lyse antibiotic-resistant E. coli, indicating that the phages can serve as a natural biocontrol of antibiotic-resistant E. coli that contaminates the river waters of Palembang City.