An in-silico approach to meniscus tissue regeneration: Modeling, numerical simulation, and experimental analysis

We develop a model the dynamics of human mesenchymal stem cells (hMSCs) and chondrocytes evolving in a nonwoven polyethylene terephtalate (PET) scaffold impregnated with hyaluron and supplied with a differentiation medium. The scaffold and the cells are assumed to be contained in a bioreactor with f...

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Veröffentlicht in:	arXiv.org 2024-03
Hauptverfasser:	Grosjean, Elise, Keilmann, Alex, Jäger, Henry, Shimi Mohanan, Redenbach, Claudia, Simeon, Bernd, Surulescu, Christina, de Roy, Luisa, Seitz, Andreas, Teixeira, Graciosa, Dauner, Martin, Linti, Carsten, Schmidt, Günter
Format:	Artikel
Sprache:	eng
Schlagworte:	Bioreactors Computed tomography Differentiation Macroscopic equations Mathematical models Polyethylene terephthalate Regeneration (physiology) Scaffolds Stem cells Tensors Tissue engineering
Online-Zugang:	Volltext
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