Synthetic morphogenesis: why reverse engineering should be prioritized

Gene regulation influence Extensive mapping of the genetic code has granted the ability to create gene regulatory networks (GRNs), which serve as control systems for morphogenetic cellular development. Advanced scaffold delivery systems Building upon existing knowledge of the complex mechanisms behi...

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Veröffentlicht in:Bio-design and manufacturing 2021-06, Vol.4 (2), p.429-431
Hauptverfasser: Nikolenko, V. N., Nikolayev, M. Yu, Sinelnikov, M. Y.
Format: Artikel
Sprache:eng
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Zusammenfassung:Gene regulation influence Extensive mapping of the genetic code has granted the ability to create gene regulatory networks (GRNs), which serve as control systems for morphogenetic cellular development. Advanced scaffold delivery systems Building upon existing knowledge of the complex mechanisms behind morphogenesis, several scaffolds have been developed to mimic the highly interconnective cell–ECM environment. 3D-printed modifications of ε-caprolactone scaffolds with microspheres embedded between their fibrils releases microsphere content throughout slow biopolymer degradation over a course of weeks [17]. [...]reverse engineering of specific morphogenetic actions from mapped genetic profiles seems to be the most feasible prospect in synthetic morphology and can be achieved with existing technology. Compliance with ethical standards Conflict of interest V. N. Nikolenko, M. Yu Nikolayev, and M. Y. Sinelnikov declare that they have no conflict of interest.
ISSN:2096-5524
2522-8552
DOI:10.1007/s42242-021-00127-6