Petal-shaped MoS2/FeS2@C nanocomposites with enhanced peroxidase-like activity for colorimetric detection of H2O2 and glutathione

In this work, we reported the FeS 2 @C nanocapsules-modified petal-shaped MoS 2 nanosheets (MoS 2 /FeS 2 @C) peroxidase prepared by arc discharging combined with hydrothermal methods. We thoroughly investigated their peroxidase-like activities in the colorimetric detection of H 2 O 2 and glutathione (GSH). The results indicate that the prepared petal-shaped MoS 2 /FeS 2 @C nanocomposites exhibit enhanced peroxidase activity compared to the single-component MoS 2 or FeS 2 @C. The detection ranges and detection limits (LOD) are 1–150 μM and 0.43 μM for H 2 O 2 , respectively, while for GSH, they are 0.2–40 μM and 0.14 μM, respectively. The superior peroxidase-like activity of the MoS 2 /FeS 2 @C results from the synergy between the MoS 2 and FeS 2 @C. This synergy creates abundant active sites and more substance shuttle channels, which increases the cyclic efficiency among Fe 3+ /Fe 2+ and Mo 6+ /Mo 4+ and improves the yield of hydroxyl radicals. As a result, the MoS 2 /FeS 2 @C nanocomposites acquired quick electron transport and improved peroxidase-like catalytic performance. Moreover, the MoS 2 /FeS 2 @C nanocomposites exhibit high stability and selectivity, retaining high-activity levels even after 30 days. These make them promising candidates for use in biosensing and catalysis applications.