Fabrication of multi-walled carbon nanotube/polycaprolactone scaffolds for possible application in tissue engineering
Flexible scaffolds made of polycaprolactone (PCL), and multi-walled carbon nanotubes (MWCNTs) were created and chemically verified through RAMAN. The most suitable coupling percentages for PCL were 1%, 3%, and 5% MWCNT. The scaffolds were very stable with high hardness values (10–12 GPa). The PCL/MW...
Gespeichert in:
Veröffentlicht in: | Journal of polymer research 2024-02, Vol.31 (2), Article 64 |
---|---|
Hauptverfasser: | , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
Zusammenfassung: | Flexible scaffolds made of polycaprolactone (PCL), and multi-walled carbon nanotubes (MWCNTs) were created and chemically verified through RAMAN. The most suitable coupling percentages for PCL were 1%, 3%, and 5% MWCNT. The scaffolds were very stable with high hardness values (10–12 GPa). The PCL/MWCNT 5% scaffold was the most flexible and least resistant, with adequate porosity, pore size, and interconnectivity for cell anchoring. Moreover, the scaffold exhibited low cytotoxicity with a cell viability of 90%. These flexible PCL/MWCNT scaffolds were developed to support tissue engineering by providing a mechanical response with flexibility and elasticity like the surrounding tissue. |
---|---|
ISSN: | 1022-9760 1572-8935 |
DOI: | 10.1007/s10965-024-03875-y |