Fabrication of multi-walled carbon nanotube/polycaprolactone scaffolds for possible application in tissue engineering

Flexible scaffolds made of polycaprolactone (PCL), and multi-walled carbon nanotubes (MWCNTs) were created and chemically verified through RAMAN. The most suitable coupling percentages for PCL were 1%, 3%, and 5% MWCNT. The scaffolds were very stable with high hardness values (10–12 GPa). The PCL/MW...

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Veröffentlicht in:Journal of polymer research 2024-02, Vol.31 (2), Article 64
Hauptverfasser: Peñaranda-Armbrecht, Jose, Correa-Quiceno, Mario Jose, Caicedo-Angulo, Julio Cesar, Neuta-Arciniegas, Paola Andrea, Gutiérrez-Montes, José Óscar
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Sprache:eng
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Zusammenfassung:Flexible scaffolds made of polycaprolactone (PCL), and multi-walled carbon nanotubes (MWCNTs) were created and chemically verified through RAMAN. The most suitable coupling percentages for PCL were 1%, 3%, and 5% MWCNT. The scaffolds were very stable with high hardness values (10–12 GPa). The PCL/MWCNT 5% scaffold was the most flexible and least resistant, with adequate porosity, pore size, and interconnectivity for cell anchoring. Moreover, the scaffold exhibited low cytotoxicity with a cell viability of 90%. These flexible PCL/MWCNT scaffolds were developed to support tissue engineering by providing a mechanical response with flexibility and elasticity like the surrounding tissue.
ISSN:1022-9760
1572-8935
DOI:10.1007/s10965-024-03875-y