Cover Feature: Transition‐Metal‐Free Synthesis of 2‐Substituted BenzoIndoles via the Reaction of 1‐Halo‐8‐lithionaphthalenes with Nitriles

The organolithium approach to the synthesis of benzo[cd]indoles. The person hanging up the washing represents organolithium reagents that promote the reaction between peri‐dihalonaphthalenes and nitriles by utilizing the so‐called “clothespin effect”. The suggested approach is a nice alternative to...

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Veröffentlicht in:Chemistry : a European journal 2024-02, Vol.30 (10)
Hauptverfasser: Tsybulin, Semyon V, Kaplanskiy, Mark V, Antonov, Alexander S
Format: Artikel
Sprache:eng
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Zusammenfassung:The organolithium approach to the synthesis of benzo[cd]indoles. The person hanging up the washing represents organolithium reagents that promote the reaction between peri‐dihalonaphthalenes and nitriles by utilizing the so‐called “clothespin effect”. The suggested approach is a nice alternative to known transition‐metal‐catalyzed reactions, making access to benzo[cd]Indoles more environmentally friendly. More information can be found in the Research Article by A. S. Antonov and co‐workers (DOI: 10.1002/chem.202303768).
ISSN:0947-6539
1521-3765
DOI:10.1002/chem.202400309