Development of Approaches for Obtaining Fluorine-Containing Derivatives of Boronated Amidines Based on the closo-Dodecaborate Anion
The reactivity of model amidines with general structure (NBu 4 )[B 12 H 11 NHC(CH 3 )HNCH(CH 2 OTos) 2 ] under nucleophilic fluorination conditions has been investigated in the study. The obtained products have been characterized using multinuclear NMR and IR spectroscopies, RP-HPLC, and high-resolu...
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| Veröffentlicht in: | Russian journal of inorganic chemistry 2023-12, Vol.68 (14), p.1923-1928 |
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| container_end_page | 1928 |
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| container_issue | 14 |
| container_start_page | 1923 |
| container_title | Russian journal of inorganic chemistry |
| container_volume | 68 |
| creator | Ryabchikova, M. N. Neumolotov, N. K. Nelyubin, A. V. Selivanov, N. A. Klyukin, I. N. Bykov, A. Yu Zhdanov, A. P. Zhizhin, K. Yu Kuznetsov, N. T. |
| description | The reactivity of model amidines with general structure (NBu
4
)[B
12
H
11
NHC(CH
3
)HNCH(CH
2
OTos)
2
] under nucleophilic fluorination conditions has been investigated in the study. The obtained products have been characterized using multinuclear NMR and IR spectroscopies, RP-HPLC, and high-resolution mass spectrometry. The results obtained can be applied in the synthesis of similar derivatives containing
18
F atoms for studying the pharmacokinetic parameters of BNCT agents using the PET method. |
| doi_str_mv | 10.1134/S0036023623603252 |
| format | Article |
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4
)[B
12
H
11
NHC(CH
3
)HNCH(CH
2
OTos)
2
] under nucleophilic fluorination conditions has been investigated in the study. The obtained products have been characterized using multinuclear NMR and IR spectroscopies, RP-HPLC, and high-resolution mass spectrometry. The results obtained can be applied in the synthesis of similar derivatives containing
18
F atoms for studying the pharmacokinetic parameters of BNCT agents using the PET method.</description><identifier>ISSN: 0036-0236</identifier><identifier>EISSN: 1531-8613</identifier><identifier>DOI: 10.1134/S0036023623603252</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Chemistry ; Chemistry and Materials Science ; Fluorination ; Fluorine ; Inorganic Chemistry ; Mass spectrometry ; NMR ; Nuclear magnetic resonance ; Synthesis and Properties of Inorganic Compounds</subject><ispartof>Russian journal of inorganic chemistry, 2023-12, Vol.68 (14), p.1923-1928</ispartof><rights>Pleiades Publishing, Ltd. 2023. ISSN 0036-0236, Russian Journal of Inorganic Chemistry, 2023, Vol. 68, No. 14, pp. 1923–1928. © Pleiades Publishing, Ltd., 2023.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c268t-234f8b81d7cdff57e05d6ba153a19085074eecaa588c727e6e0ea727f2808d623</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1134/S0036023623603252$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1134/S0036023623603252$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,776,780,27901,27902,41464,42533,51294</link.rule.ids></links><search><creatorcontrib>Ryabchikova, M. N.</creatorcontrib><creatorcontrib>Neumolotov, N. K.</creatorcontrib><creatorcontrib>Nelyubin, A. V.</creatorcontrib><creatorcontrib>Selivanov, N. A.</creatorcontrib><creatorcontrib>Klyukin, I. N.</creatorcontrib><creatorcontrib>Bykov, A. Yu</creatorcontrib><creatorcontrib>Zhdanov, A. P.</creatorcontrib><creatorcontrib>Zhizhin, K. Yu</creatorcontrib><creatorcontrib>Kuznetsov, N. T.</creatorcontrib><title>Development of Approaches for Obtaining Fluorine-Containing Derivatives of Boronated Amidines Based on the closo-Dodecaborate Anion</title><title>Russian journal of inorganic chemistry</title><addtitle>Russ. J. Inorg. Chem</addtitle><description>The reactivity of model amidines with general structure (NBu
4
)[B
12
H
11
NHC(CH
3
)HNCH(CH
2
OTos)
2
] under nucleophilic fluorination conditions has been investigated in the study. The obtained products have been characterized using multinuclear NMR and IR spectroscopies, RP-HPLC, and high-resolution mass spectrometry. The results obtained can be applied in the synthesis of similar derivatives containing
18
F atoms for studying the pharmacokinetic parameters of BNCT agents using the PET method.</description><subject>Chemistry</subject><subject>Chemistry and Materials Science</subject><subject>Fluorination</subject><subject>Fluorine</subject><subject>Inorganic Chemistry</subject><subject>Mass spectrometry</subject><subject>NMR</subject><subject>Nuclear magnetic resonance</subject><subject>Synthesis and Properties of Inorganic Compounds</subject><issn>0036-0236</issn><issn>1531-8613</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNp1kE9LAzEQxYMoWKsfwFvA82qS_Zcet61VQehBPS_Z3Um7ZZtZk23Bs1_cKVU8iBCYZOb3XpjH2LUUt1LGyd2LEHEmVJzREbFK1QkbyTSWkc5kfMpGh3F0mJ-zixA2QiSJyPWIfc5hDx32W3ADR8uLvvdo6jUEbtHzZTWY1rVuxRfdDn3rIJqh--nNwbd7M7R7okk7RY_ODNDwYts2xAY-NYGe6PiwBl53GDCaYwO1qdATyQvXortkZ9Z0Aa6-65i9Le5fZ4_R8_LhaVY8R7XK9BCpOLG60rLJ68baNAeRNlllaEsjJ0KnIk-AnE2qdZ2rHDIQYOhilRa6oWDG7OboSyu-7yAM5QZ33tGXpZoo0qtEpETJI1V7DMGDLXvfbo3_KKUoD1mXf7ImjTpqArFuBf7X-X_RFxQsgbI</recordid><startdate>20231201</startdate><enddate>20231201</enddate><creator>Ryabchikova, M. N.</creator><creator>Neumolotov, N. K.</creator><creator>Nelyubin, A. V.</creator><creator>Selivanov, N. A.</creator><creator>Klyukin, I. N.</creator><creator>Bykov, A. Yu</creator><creator>Zhdanov, A. P.</creator><creator>Zhizhin, K. Yu</creator><creator>Kuznetsov, N. T.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20231201</creationdate><title>Development of Approaches for Obtaining Fluorine-Containing Derivatives of Boronated Amidines Based on the closo-Dodecaborate Anion</title><author>Ryabchikova, M. N. ; Neumolotov, N. K. ; Nelyubin, A. V. ; Selivanov, N. A. ; Klyukin, I. N. ; Bykov, A. Yu ; Zhdanov, A. P. ; Zhizhin, K. Yu ; Kuznetsov, N. T.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-234f8b81d7cdff57e05d6ba153a19085074eecaa588c727e6e0ea727f2808d623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Chemistry</topic><topic>Chemistry and Materials Science</topic><topic>Fluorination</topic><topic>Fluorine</topic><topic>Inorganic Chemistry</topic><topic>Mass spectrometry</topic><topic>NMR</topic><topic>Nuclear magnetic resonance</topic><topic>Synthesis and Properties of Inorganic Compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ryabchikova, M. N.</creatorcontrib><creatorcontrib>Neumolotov, N. K.</creatorcontrib><creatorcontrib>Nelyubin, A. V.</creatorcontrib><creatorcontrib>Selivanov, N. A.</creatorcontrib><creatorcontrib>Klyukin, I. N.</creatorcontrib><creatorcontrib>Bykov, A. Yu</creatorcontrib><creatorcontrib>Zhdanov, A. P.</creatorcontrib><creatorcontrib>Zhizhin, K. Yu</creatorcontrib><creatorcontrib>Kuznetsov, N. T.</creatorcontrib><collection>CrossRef</collection><jtitle>Russian journal of inorganic chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Ryabchikova, M. N.</au><au>Neumolotov, N. K.</au><au>Nelyubin, A. V.</au><au>Selivanov, N. A.</au><au>Klyukin, I. N.</au><au>Bykov, A. Yu</au><au>Zhdanov, A. P.</au><au>Zhizhin, K. Yu</au><au>Kuznetsov, N. T.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Development of Approaches for Obtaining Fluorine-Containing Derivatives of Boronated Amidines Based on the closo-Dodecaborate Anion</atitle><jtitle>Russian journal of inorganic chemistry</jtitle><stitle>Russ. J. Inorg. Chem</stitle><date>2023-12-01</date><risdate>2023</risdate><volume>68</volume><issue>14</issue><spage>1923</spage><epage>1928</epage><pages>1923-1928</pages><issn>0036-0236</issn><eissn>1531-8613</eissn><abstract>The reactivity of model amidines with general structure (NBu
4
)[B
12
H
11
NHC(CH
3
)HNCH(CH
2
OTos)
2
] under nucleophilic fluorination conditions has been investigated in the study. The obtained products have been characterized using multinuclear NMR and IR spectroscopies, RP-HPLC, and high-resolution mass spectrometry. The results obtained can be applied in the synthesis of similar derivatives containing
18
F atoms for studying the pharmacokinetic parameters of BNCT agents using the PET method.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S0036023623603252</doi><tpages>6</tpages></addata></record> |
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| issn | 0036-0236 1531-8613 |
| language | eng |
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| source | SpringerLink Journals |
| subjects | Chemistry Chemistry and Materials Science Fluorination Fluorine Inorganic Chemistry Mass spectrometry NMR Nuclear magnetic resonance Synthesis and Properties of Inorganic Compounds |
| title | Development of Approaches for Obtaining Fluorine-Containing Derivatives of Boronated Amidines Based on the closo-Dodecaborate Anion |
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