Disturbances of carbohydrate metabolism and factors stimulating its development in ontogenesis

The review contains comprehensive data from the literature about the effect of unfavorable factors on forming an insular apparatus of the pancreas and the development of the disturbances of carbohydrate metabolism in ontogenesis. The analyses of current sources showed that the effect of unfavorable factors in the embryonic period and early childhood defines the development of some disturbances of carbohydrate metabolism in adult life. In the process of ontogenesis, the combination of the reduction of the insular apparatus’s functional activity and risk factors (age, overweight, stress, hypodynamia) can lead to the development of metabolic syndrome, diabetes mellitus, and obesity.