Effects of Hyper- and Hypothermia on Hemodynamic Parameters in People of Different Age Groups: Meta-Analysis

Age-related changes in thermoregulation occur due to deterioration of the adaptive capacity of the cardiovascular system, which is caused by remodeling of the vascular wall and myocardium, reduced capillary density, changes in the synthesis and clearance of neurotransmitters and vasoactive substances, and the inhibition of the autonomic mechanisms of regulation of the hemodynamic parameters. A common method to simulate hyper- and hypothermal conditions is to use a suit with tubes filled with water at different temperatures. The goal of this work was to conduct a meta-analysis of the hemodynamic parameters shifts in the modeling of hyper- and hypothermia with such a suit in people of different age groups. It was found that whole-body heating is accompanied by a decrease in blood pressure (BP) and an increase in heart rate (HR). The reaction of hemodynamic parameters to hyperthermia does not significantly change with aging. Whole-body cooling is accompanied by an increase in BP without a change in the HR. With hypothermia, the amplitude of the increase in the systolic BP is more pronounced in older people.