Histometric Symptoms of Age-Sensitive Changes of Bone Tissue

This study presents the results of complex histomorphometric research of the features of age-related dynamics of bone tissue. We used as study material samples of the distal epiphysis and diaphysis of the left tibia from 348 male corpses aging from 0 to 90 years. The group of microosteometric features that have the strongest correlation with age is established in different age groups; their quantitative characteristics are given here. It has been clarified that the trends of age-related changes in the structural components of bone tissue correspond to the basic patterns of growth, remodeling, and depend on the species and their localization. Conceptual positions of age involution of bone tissue are proposed in this study.