Effects of Electroacupuncture on the Ability of Learning and Memory in Rats with Ischemia-reperfusion Injury

Objective To observe the effects of pretreatment and treatment with electroacupuncture on the ability of learning and memory in rats with ischemia-reperfusion injury, and to provide the research basis for preventing and treating the disorder of learning and memory in patients with apoplectic sequelae. Methods Seventy-two SD rats, clean class, were randomly divided into sham operation group, model group, pretreatment group, and treatment group. The step-through latency and number of errors, nerve injury score, and the number of cholinoceptor in the affected hippocampus were recorded to analyze the effects of pretreatment and treatment with electroacupuncture on the ability of learning and memory in rats with ischemia-reperfusion injury. Results 1) The rats with ischemia had various signs of nerve injury. Compared with that in the sham operation rats, the nerve injury score in the model rats was lower, the step-through latency and number of errors were increased, and the content of special mAchR was decreased ( P