Controllable Adaptive Molybdate‐Oligosaccharide Nanoparticles Regulate M2 Macrophage Mitochondrial Function and Promote Angiogenesis via PI3K/HIF‐1α/VEGF Pathway to Accelerate Diabetic Wound Healing (Adv. Healthcare Mater. 3/2024)

Molybdate‐Oligosaccharide Nanosystem The powerful molybdate‐oligosaccharide nanosystem (CMO) exhibit pH‐responsive release Mo2+ and oligosaccharide to enhance mitochondrial function and facilitate the transition of macrophages from M1 to M2 phenotype. In article 2302256, Xiuhong Huang, Shaohong Huang, and co‐workers show that within an anti‐inflammatory microenvironment, CMO promote angiogenesis through activation of the PI3K/HIF‐1α/VEGF pathway. Such a pH‐responsive nanosystem with immunomodulatory properties and angiogenesis‐ and mitochondrial‐promotion capacity presents a promising potential for diabetic wounds repair.