Label-free detection repeatability of protein microarrays by oblique-incidence reflectivity difference method

We examine the repeatabilities of oblique-incidence reflectivity difference（OIRD） method for label-free detecting biological molecular interaction using protein microarrays.The experimental results show that the repeatabilities are the same in a given microarray or microarray-microarray and are cons...

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Veröffentlicht in:	Science China. Physics, mechanics & astronomy mechanics & astronomy, 2012-12, Vol.55 (12), p.2347-2350
Hauptverfasser:	Dai, Jun, Li, Lin, Wang, JingYi, He, LiPing, Lu, HuiBin, Ruan, KangCheng, Jin, KuiJuan, Yang, GuoZhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Astronomy Classical and Continuum Physics Labels Molecular interactions Observations and Techniques Physics Physics and Astronomy Proteins Reflectance 反射率可重复性斜入射无标记检测生物芯片技术蛋白质微阵列蛋白质芯片
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Zusammenfassung:	We examine the repeatabilities of oblique-incidence reflectivity difference（OIRD） method for label-free detecting biological molecular interaction using protein microarrays.The experimental results show that the repeatabilities are the same in a given microarray or microarray-microarray and are consistent,indicating that OIRD is a promising label-free detection technique for biological microarrays.
ISSN:	1674-7348 1869-1927
DOI:	10.1007/s11433-012-4952-x