An Adaptive Algorithm for Machine Perfusion of Isolated Donor Liver

A hardware and software system for donor liver perfusion is described. Both standard and adaptive algorithms for perfusion control in the process of liver function restoration are described. The adaptive algorithm is based on a mathematical model of machine perfusion. It provides complete perfusion...

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Veröffentlicht in:	Biomedical engineering 2018-03, Vol.51 (6), p.401-406
Hauptverfasser:	Gryaznov, N. A., Kharlamov, V. V., Gataulin, Ya. A., Yukhnev, A. D., Shumilov, A. V., Nikitin, S. A., Senchik, K. Yu, Reznik, O. N., Skvortsov, A. E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptive algorithms Adaptive control Algorithms Arterial lines Biomaterials Biomedical Engineering and Bioengineering Blood Blood cells Control algorithms Disadvantages Engineering Heat transfer Injury prevention Liver Mathematical models Perfusion Pipelines Restoration Sensors Software Surgical apparatus & instruments Veins & arteries Viscosity
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Beschreibung
Zusammenfassung:	A hardware and software system for donor liver perfusion is described. Both standard and adaptive algorithms for perfusion control in the process of liver function restoration are described. The adaptive algorithm is based on a mathematical model of machine perfusion. It provides complete perfusion and allows blood cell injuries that often accompany the standard perfusion procedure to be avoided.
ISSN:	0006-3398 1573-8256
DOI:	10.1007/s10527-018-9758-3