Biological Optimization of Dose Distribution to Reduce the Patient Radiation Exposure during Hypofractionated Radiation Therapy

Biological Optimization of Dose Distribution to Reduce the Patient Radiation Exposure during Hypofractionated Radiation Therapy

The results of inverse dosimetric planning of intensity-modulated photon radiation therapy are presented. Physical and biological weight functions were used to optimize the dose distribution. Irradiation plans based on biological optimization functions were shown to have advantages over plans based...

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Veröffentlicht in:Biomedical engineering 2022, Vol.55 (5), p.360-364
Hauptverfasser: Sukhikh, E. S., Sukhikh, L. G.
Format: Artikel
Sprache:eng
Schlagworte:
Biomaterials
Biomedical and Life Sciences
Biomedicine
Cancer therapies
Dosimetry
Engineering
Mathematical optimization
Optimization
Planning
Prostate cancer
Radiation
Radiation dosage
Radiation effects
Radiation therapy
Radiotherapy
Weighting functions
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Beschreibung
Zusammenfassung:The results of inverse dosimetric planning of intensity-modulated photon radiation therapy are presented. Physical and biological weight functions were used to optimize the dose distribution. Irradiation plans based on biological optimization functions were shown to have advantages over plans based on physical optimization for achieving the goal of radiation therapy, as well as reducing radiation exposure and the time required to calculate the dose distribution.
ISSN:0006-3398
1573-8256
DOI:10.1007/s10527-022-10136-z