KA2 and A3 coupling reactions promoted by Fe3O4@T-CS@Cys@Ag+ nanocomposite

Chitosan biopolymer was functionalized with cysteine amino acid via trichloro-1,3,5-triazine-bridged agent. The magnetization process was done due to the treatment of functionalized chitosan with iron oxide nanoparticles. In the final nanocomposite (Fe 3 O 4 @T-CS@Cys@Ag + ), thiol and carboxylate groups of cysteine were surrounded by silver ions. The catalytic activity of the prepared nanocomposite was studied in KA 2 and A 3 coupling reactions for the synthesis of propargylamines.