Hemocompatibility, swelling and thermal properties of hydrogels based on 2-hydroxyethyl acrylate, itaconic acid and poly(ethylene glycol) dimethacrylate

Two series of novel hydrogels, based on 2-hydroxyethyl acrylate (HEA), itaconic acid (IA), and two poly(ethylene glycol) dimethacrylates (PEGDMA), of different ethylene glycol chain lengths, were prepared by free radical crosslinking copolymerization. The influence of different ethylene glycol chain...

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Veröffentlicht in:	Polymer bulletin (Berlin, Germany) Germany), 2013-10, Vol.70 (10), p.2895-2909
Hauptverfasser:	TOMIC, Simonida L.J, JOVASEVIC, Jovana S, FILIPOVIC, Jovanka M
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Biocompatibility Biological and medical sciences Biomedical materials Characterization and Evaluation of Materials Chemistry Chemistry and Materials Science Complex Fluids and Microfluidics Contact Copolymerization Copolymers Crosslinking Exact sciences and technology Flexibility Free radicals Glass transition temperature Glycol dimethacrylates Hydrogels Hydroxyethyl acrylate In vitro methods and tests Itaconic acid Medical sciences Molecular weight Organic Chemistry Organic polymers Original Paper Physical Chemistry Physicochemistry of polymers Physiology Polyethylene glycol Polymer Sciences Polymerization Polymers Potassium Properties and characterization Soft and Granular Matter Solution and gel properties Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Swelling Technology. Biomaterials. Equipments Temperature Thermodynamic properties
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Zusammenfassung:	Two series of novel hydrogels, based on 2-hydroxyethyl acrylate (HEA), itaconic acid (IA), and two poly(ethylene glycol) dimethacrylates (PEGDMA), of different ethylene glycol chain lengths, were prepared by free radical crosslinking copolymerization. The influence of different ethylene glycol chain lengths and concentration in P(HEA/IA/PEGDMA) hydrogels on biocompatibility, swelling and thermal properties was investigated. All samples in contact with blood showed a mean hemolysis value
ISSN:	0170-0839 1436-2449
DOI:	10.1007/s00289-013-0995-z