Highly Deformable Double‐Sided Neural Probe with All‐in‐One Electrode System for Real‐Time In Vivo Detection of Dopamine for Parkinson's Disease (Adv. Funct. Mater. 4/2024)

Neural Probes In article number 2311436, Yong‐Seok Oh, Kyung‐In Jang, and co‐workers present a multi‐deformable double‐sided (MDD) probe that facilitates real‐time dopamine monitoring in the brain. The all‐in‐one probe integrates working, reference, and counter electrodes, achieving high sensitivity and selectivity through enzyme immobilization on ZnO nanorods. Its serpentine design ensures stretchability and stress management. Successful rodent implantation enables reliable in‐vivo monitoring of dopamine dynamics, including assessing L‐DOPA treatment effects in hemi‐PD mice.