A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue (Adv. Mater. 3/2024)

Bioadhesives In article number 2307288, Ellen T. Roche and co‐workers introduce a silicone‐based bioadhesive tailored for robust, durable adhesion between silicone devices and biological tissues. The strategy addresses the challenges of wet tissue adhesion and long‐term integration by blending soft silicone oligomers, siloxane coupling agents, and absorbents. The adhesive undergoes controlled degradation, transitioning from nonpermeable to permeable, fostering cell migration and ensuring effective adhesion in diverse medical device applications.