The Impact of High D-Dimer on The Clinical Outcome of Covid-19 patients at A Private Hospital in Jakarta

D-Dimer is a fibrin degradation product as the resultof thrombus degradation by fibrinolysis. Elevated D-dimer in the blood is a presumptive marker of thrombosis. D-dimer levels above 1g/mL are risk factors for poorprognosis in patients with COVID-19. To evaluate the impact of high D-Dimer on the cl...

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Veröffentlicht in:Research journal of pharmacy and technology 2023-08, Vol.16 (8), p.3773-3779
Hauptverfasser: Laila Ramatillah, Diana, Ainah, Nona, Michael, Michael, Kasim, Fauzi, Purwati, Purwati, Khan, Kashifullah
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Sprache:eng
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Zusammenfassung:D-Dimer is a fibrin degradation product as the resultof thrombus degradation by fibrinolysis. Elevated D-dimer in the blood is a presumptive marker of thrombosis. D-dimer levels above 1g/mL are risk factors for poorprognosis in patients with COVID-19. To evaluate the impact of high D-Dimer on the clinical outcome of Covid-19 patients at Private Hospital in Jakarta. A retrospective cohort study with convenience sampling was applied in this study. There were 980 patients but only 320 patients were eligible for inclusion criteria. This study only included confirmed COVID-19 patients who were hospitalized from March to June 2021, and the study was conducted from March to June 2022. The gender of the majority patients as the sample was male, 165 (52%) and 155(48%) female patients with moderate severity. Correlation between D-dimer and clinical outcome of COVID-19 patients using Fisher's exact method showed a higher survival rate of 287(89.7%) patients compared to 33(10.3%) patients who died with a p-value
ISSN:0974-3618
0974-360X
0974-306X
DOI:10.52711/0974-360X.2023.00623