Chemical and physiological effects of dexamethasone drug to hyperglycemia with Covid-19 patients

The great spread during the last three years of (COVID˗19) pandemic and sudden genetic mutations represented a challenge to reach a definitive drug or vaccine for it. ±Treatment options promised to stand out as potential therapy, including plasma-derived drugs, monoclonal antibodies, antivirals, cel...

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Hauptverfasser: Hamzah, Ahmed Ibrahim, Algburi, Jaafar B., Mohsin, Dheyaa Hussein, Alasedi, Kasim Kadhim, AL-Mayah, Saif Jabbar Yasir, Radhdi, Ali Jabbar
Format: Tagungsbericht
Sprache:eng
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Zusammenfassung:The great spread during the last three years of (COVID˗19) pandemic and sudden genetic mutations represented a challenge to reach a definitive drug or vaccine for it. ±Treatment options promised to stand out as potential therapy, including plasma-derived drugs, monoclonal antibodies, antivirals, cell therapy, and corticosteroids. Decadron sone is an anti-inflammatory and immunosuppressive corticosteroid drug that has been licensed by the FDA. We are still at risk from the (COVID19) pandemic. Despite advances in treatment, steroids are still the gold standard for treating severe disease, and they come with side effects such immunosuppression and hyperglycemia. Acute hyperglycaemia care in critically sick and non-critically ill patients is critical for boosting infection recovery rates and lowering mortality. In this situation, managing hyperglycaemia necessitates a distinct set of skills, including a stronger theoretical and practical understanding of insulin administration. This article attempts to raise physician awareness about appropriate hyperglycaemia management. The present work included a follow-up set of patient’s health infected with (COVID˗19) for four months, from their admission Hassan Halos Al-Hatemy Specialist Hospital for Transmitted Diseases, Najaf, Iraq until their recovery and after recovery. Based upon monitoring one hundred patients suffering from severe suffocation in breathing, whose is treated with given doses of Decadron. Then the correlation to the dose of Decadron given and the hyperglycemia was explained according to obtained results. 66% of patients were non-diabetic and 34% were diabetic before infection with (COVID˗19). The chemical and physiological factors that affect blood sugar levels were examined. The outcomes show that the blood sugar level exhibits a turbulent increasing relationship with Decadron doses for all samples The daily obtained statistical results were investigated and discussed, to explain the turbulent correlation between the level of sugar and the amount of medication taken, and them.
ISSN:0094-243X
1551-7616
DOI:10.1063/5.0183053