Septicemia and Antibiotic Susceptibility Patterns of Isolates in Tertiary Care Hospital of North India: A Deviated Trend

The present study goal was to assess the bacteriological delineation of septicaemia, as well as their antibiotic susceptibility patterns. With a clinical study of septicaemia patients, blood cultures were conducted on all suspected individual admitted to the hospital. Antibiotic sensitivity testing was done using the Kirby-Bauer disc diffusion method, and the isolated organism was identified using standard microbiological protocol. Bacterial growth was seen in 49 of the 410 specimens (10.8 percent). Gram negative isolates were responsible for majority of the septicaemia cases 33. (67.3 percent). The most commonly isolated organism was Escherichia coli, which accounted for 30.6 percent of all isolates, followed by Staphylococcus aureus, which accounted for 9.(18.3 percent). Meropenem, amikacin, Vancomycin, teicoplanin, and susceptibility was highest in Coagulase-negative staphylococci as well as Staphylococcus aureus. ofloxacin, piperacillin/tazobactam, meropenem, gentamicin and amikacin susceptibility were found in Gram-negative isolates. According to the study, the most common and emerging pathogens responsible for septicemia in a tertiary care clinical context are Escherichia coli and Staphylococcus aureus and both show resistance to routinely used antibiotics