Statistical Optimization of Microwave Assisted Acrylamide Grafting of Linum usitatissimum Gum
Polymer designing being the emerging tool in formulating novel and green dosage systems. While using a polymer derived from natural source one can contribute in number of ways as these polymers have comparatively lesser toxicity, are easy to ingest and bio compatible in nature. In the current study...
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| Veröffentlicht in: | NeuroQuantology 2022-01, Vol.20 (11), p.4008 |
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| creator | Sahu, Pratibha Sharma, Govind Vinay Sagar Verma Mishra, Aditya Deshmukh, Neeraj Pandey, Ajit Tripathi, Arpan Kumar Pradhan, Dusmanta Kumar Chauhan, Pradeep |
| description | Polymer designing being the emerging tool in formulating novel and green dosage systems. While using a polymer derived from natural source one can contribute in number of ways as these polymers have comparatively lesser toxicity, are easy to ingest and bio compatible in nature. In the current study we extracted gum from plant Linum usitatissimum(flax seed) and subjected it to microwave radiation induced grafting method for formulation of a grafted polymer with acrylamide. The optimization of this grafted polymer is done using various statistical methods to get the best possible composition to get best efficacy while monitoring ingestion and least toxicity profile.The task of optimization of reaction and to minimize the cost of developing and defining such optimized condition leading to yield product desired in high yield and of high purity can be achieved by the use of statistical software. |
| doi_str_mv | 10.14704/nq.2022.20.11.NQ66404 |
| format | Article |
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While using a polymer derived from natural source one can contribute in number of ways as these polymers have comparatively lesser toxicity, are easy to ingest and bio compatible in nature. In the current study we extracted gum from plant Linum usitatissimum(flax seed) and subjected it to microwave radiation induced grafting method for formulation of a grafted polymer with acrylamide. The optimization of this grafted polymer is done using various statistical methods to get the best possible composition to get best efficacy while monitoring ingestion and least toxicity profile.The task of optimization of reaction and to minimize the cost of developing and defining such optimized condition leading to yield product desired in high yield and of high purity can be achieved by the use of statistical software.</description><identifier>EISSN: 1303-5150</identifier><identifier>DOI: 10.14704/nq.2022.20.11.NQ66404</identifier><language>eng</language><publisher>Bornova Izmir: NeuroQuantology</publisher><subject>Acrylamide ; Biocompatibility ; Custom design ; Flax ; Fourier transforms ; Free radicals ; Grafting ; Hydrogels ; Ingestion ; Microwaves ; Optimization ; Pharmaceutical industry ; Pharmaceutical sciences ; Pharmacy ; Polymers ; Radiation ; Radiation effects ; Scanning electron microscopy ; Spectrum analysis ; Statistical methods ; Toxicity</subject><ispartof>NeuroQuantology, 2022-01, Vol.20 (11), p.4008</ispartof><rights>Copyright NeuroQuantology 2022</rights><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids></links><search><creatorcontrib>Sahu, Pratibha</creatorcontrib><creatorcontrib>Sharma, Govind</creatorcontrib><creatorcontrib>Vinay Sagar Verma</creatorcontrib><creatorcontrib>Mishra, Aditya</creatorcontrib><creatorcontrib>Deshmukh, Neeraj</creatorcontrib><creatorcontrib>Pandey, Ajit</creatorcontrib><creatorcontrib>Tripathi, Arpan Kumar</creatorcontrib><creatorcontrib>Pradhan, Dusmanta Kumar</creatorcontrib><creatorcontrib>Chauhan, Pradeep</creatorcontrib><title>Statistical Optimization of Microwave Assisted Acrylamide Grafting of Linum usitatissimum Gum</title><title>NeuroQuantology</title><description>Polymer designing being the emerging tool in formulating novel and green dosage systems. 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The optimization of this grafted polymer is done using various statistical methods to get the best possible composition to get best efficacy while monitoring ingestion and least toxicity profile.The task of optimization of reaction and to minimize the cost of developing and defining such optimized condition leading to yield product desired in high yield and of high purity can be achieved by the use of statistical software.</description><subject>Acrylamide</subject><subject>Biocompatibility</subject><subject>Custom design</subject><subject>Flax</subject><subject>Fourier transforms</subject><subject>Free radicals</subject><subject>Grafting</subject><subject>Hydrogels</subject><subject>Ingestion</subject><subject>Microwaves</subject><subject>Optimization</subject><subject>Pharmaceutical industry</subject><subject>Pharmaceutical sciences</subject><subject>Pharmacy</subject><subject>Polymers</subject><subject>Radiation</subject><subject>Radiation effects</subject><subject>Scanning electron microscopy</subject><subject>Spectrum analysis</subject><subject>Statistical methods</subject><subject>Toxicity</subject><issn>1303-5150</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>BENPR</sourceid><recordid>eNqNjt1qAjEQhYMgaNVXkECv3U72l72UUvWiVURvRcKalZFNopnEUp--aekD9OYc5pyP4TA2FZCIvIL8xdySFNI0SiJEst6WZQ55jw1FBtmsEAUM2BPRBaCooC6H7LDz0iN5bGTHN1ePGh8xsIbbln9g4-ynvCs-J4qQOvF54746qfGk-NLJ1qM5_5DvaILmgfD3G6GO1zLoMeu3siM1-fMRe1687V9Xs6uzt6DIHy82OBOrY1qDqOoqDsv-R30D7URKlA</recordid><startdate>20220101</startdate><enddate>20220101</enddate><creator>Sahu, Pratibha</creator><creator>Sharma, Govind</creator><creator>Vinay Sagar Verma</creator><creator>Mishra, Aditya</creator><creator>Deshmukh, Neeraj</creator><creator>Pandey, Ajit</creator><creator>Tripathi, Arpan Kumar</creator><creator>Pradhan, Dusmanta Kumar</creator><creator>Chauhan, Pradeep</creator><general>NeuroQuantology</general><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88G</scope><scope>8FE</scope><scope>8FG</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>ARAPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BGLVJ</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>M0S</scope><scope>M2M</scope><scope>P5Z</scope><scope>P62</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope></search><sort><creationdate>20220101</creationdate><title>Statistical Optimization of Microwave Assisted Acrylamide Grafting of Linum usitatissimum Gum</title><author>Sahu, Pratibha ; 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| source | Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Acrylamide Biocompatibility Custom design Flax Fourier transforms Free radicals Grafting Hydrogels Ingestion Microwaves Optimization Pharmaceutical industry Pharmaceutical sciences Pharmacy Polymers Radiation Radiation effects Scanning electron microscopy Spectrum analysis Statistical methods Toxicity |
| title | Statistical Optimization of Microwave Assisted Acrylamide Grafting of Linum usitatissimum Gum |
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