INFLAMMATORY BOWEL DISEASES AND NUTRIGENOMICS: IMPORTANCE, PREVENTION AND TREATMENT: A REVIEW

Inflammatory bowel diseases (IBDs) are chronic illnesses that affect not only the gut and gastrointestinal tract, but also the extraintestinal organs in many people. The primary reasons for this are changes in diet, genetic makeup, and environmental factors. The gradually changing diet is increasing the risk of the disease and increasing its severity. The immune system of the gut is affected, and the risk of the disease increases by increasing the permeability of the mucosal layer. The dietary changes interfere with the immune system, and the disease accelerates. The dietary pattern and the micronutrients are reviewed to understand the treatment procedure. Later, future interventions are considered for the treatment of inflammatory bowel disease. The genetic makeup of humans also plays a significant role in the development of this disease. Heredity also plays an important role in the inflammation of the gut. Many treatment procedures and recent studies have found many resolving issues to prevent inflammatory bowel disease. The genetic makeup cannot be changed, but the microbiome can be modified accordingly to prevent the inflammation of the gut. This review examines the role of nutrition, genetics, and phytonutrients in IBD treatment.