Citrullus Lanatus Seed Extract Ameliorates Hematological and Oxidative Stress Disorders in Lead-Induced Toxicity in Rats

Citrullus Lanatus Seed Extract Ameliorates Hematological and Oxidative Stress Disorders in Lead-Induced Toxicity in Rats

Lead (Pb) is one of the major causes of oxidative damage. This study evaluated the effect of Citrullus lanatus (watermelon) seed extract (CLSE) on hematological and oxidative stress biomarkers in rats following exposure to lead. Wistar rats were assigned to 5 groups ( n  = 5); group 1 Control, group...

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Veröffentlicht in:Proceedings of the National Academy of Sciences, India. Section B: Biological sciences India. Section B: Biological sciences, 2023-12, Vol.93 (4), p.801-807
Hauptverfasser: Udo, Ekerette Sampson, Okon, Idara Asuquo, Beshel, Justin Atiang, Ujong, Gabriel Otu, Owu, Daniel Udofia, Eno, Asim Ekaha
Format: Artikel
Sprache:eng
Schlagworte:
Acetic acid
Behavioral Sciences
Biomedical and Life Sciences
Erythrocytes
Glutathione
Hematological diseases
Hematology
Lead
Leukocytes
Life Sciences
Nucleic Acid Chemistry
Oxidative stress
Plant Biochemistry
Research Article
Superoxide dismutase
Toxicity
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Zusammenfassung:Lead (Pb) is one of the major causes of oxidative damage. This study evaluated the effect of Citrullus lanatus (watermelon) seed extract (CLSE) on hematological and oxidative stress biomarkers in rats following exposure to lead. Wistar rats were assigned to 5 groups ( n  = 5); group 1 Control, group 2 received 120 mg/kg Pb acetate only, group 3 received 200 mg/kg ethanol seed extract of CLSE only, group 4 received Pb acetate and CLSE (120 mg/kg + 200 mg/kg), group 5 received Pb and CLSE (120 mg/kg + 400 mg/kg). Pb caused a decrease ( p  
ISSN:0369-8211
2250-1746
DOI:10.1007/s40011-023-01477-0