Obesity and Postmenopausal Hormone Receptor-positive Breast Cancer: Epidemiology and Mechanisms

Obesity and Postmenopausal Hormone Receptor-positive Breast Cancer: Epidemiology and Mechanisms

Obesity is a potential risk for several cancers, including postmenopausal, hormone dependent breast cancers. In this review, we summarize recent studies on the impact of obesity on postmenopausal women’s health and discuss several mechanisms that were proposed to increase the risk of breast carcinog...

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Veröffentlicht in:Endocrinology (Philadelphia) 2021-12, Vol.162 (12)
Hauptverfasser: Zuo, Qianying, Band, Shoham, Kesavadas, Mrinali, Madak Erdogan, Zeynep
Format: Artikel
Sprache:eng
Schlagworte:
Breast cancer
Breast Neoplasms - epidemiology
Breast Neoplasms - etiology
Carcinogenesis
Carcinogens
Endocrinology
Epidemiology
Female
Health risks
Humans
Middle Aged
Obesity
Obesity - complications
Obesity - epidemiology
Post-menopause
Postmenopause - physiology
Receptors, Estrogen - genetics
Receptors, Estrogen - metabolism
Risk Factors
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Beschreibung
Zusammenfassung:Obesity is a potential risk for several cancers, including postmenopausal, hormone dependent breast cancers. In this review, we summarize recent studies on the impact of obesity on postmenopausal women’s health and discuss several mechanisms that were proposed to increase the risk of breast carcinogenesis.
ISSN:0013-7227
1945-7170
DOI:10.1210/endocr/bqab195