Furosemide clearance in very preterm neonates early in life: A pilot study using scavenged samples

Furosemide clearance in very preterm neonates early in life: A pilot study using scavenged samples

Background Furosemide is an off‐label drug, frequently used as a diuretic in neonates with oliguria and/or edema. Its clearance in preterm neonates is lower than in term neonates or children. We aimed, herein, to clarify furosemide clearance (CL) in very preterm (VP) neonates (

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Veröffentlicht in:Pediatrics international 2022-01, Vol.64 (1), p.e14735-n/a
Hauptverfasser: Okazaki, Kaoru, Fukuoka, Noriyasu, Kuboi, Toru, Unemoto, Jun, Kondo, Masatoshi, Kusaka, Takashi, Itoh, Susumu
Format: Artikel
Sprache:eng
Schlagworte:
Bayes Theorem
Bayesian analysis
Child
Creatinine
Diuretics
Edema
Furosemide
Humans
infant
Infant, Extremely Premature
Infant, Newborn
Intravenous administration
Liquid chromatography
neonatal intensive care units
Neonates
Off-Label Use
Pediatrics
Pharmacokinetics
Pilot Projects
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Zusammenfassung:Background Furosemide is an off‐label drug, frequently used as a diuretic in neonates with oliguria and/or edema. Its clearance in preterm neonates is lower than in term neonates or children. We aimed, herein, to clarify furosemide clearance (CL) in very preterm (VP) neonates (
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.14735