A child with CARD14‐associated papulosquamous eruption (CAPE) successfully treated with ustekinumab

A child with CARD14‐associated papulosquamous eruption (CAPE) successfully treated with ustekinumab

CARD14‐associated papulosquamous eruption (CAPE) is a rare inflammatory skin eruption that can have features of psoriasis, pityriasis rubra pilaris, and erythroderma. This skin condition is known for its resistance to topical or conventional systemic therapies. Successful treatment of CAPE with anti...

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Veröffentlicht in:Pediatric dermatology 2023-11, Vol.40 (6), p.1104-1106
Hauptverfasser: Nogueira, Miguel, Reis, Joel, Abreu, Maria, Coelho, André, Reis, Cláudia F., Machado, Susana
Format: Artikel
Sprache:eng
Schlagworte:
CARD Signaling Adaptor Proteins
Child
Child, Preschool
Dermatitis, Exfoliative
Dermatologic Agents - therapeutic use
erythroderma
Female
Guanylate Cyclase
Humans
Inflammation
Membrane Proteins
Monoclonal antibodies
pediatric
Pediatrics
Pityriasis
Pityriasis Rubra Pilaris - drug therapy
Psoriasis
Psoriasis - drug therapy
Skin diseases
Skin eruptions
ustekinumab
Ustekinumab - therapeutic use
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Zusammenfassung:CARD14‐associated papulosquamous eruption (CAPE) is a rare inflammatory skin eruption that can have features of psoriasis, pityriasis rubra pilaris, and erythroderma. This skin condition is known for its resistance to topical or conventional systemic therapies. Successful treatment of CAPE with anti‐IL‐12/IL‐23 and IL‐17 inhibitors has been reported. We present a case of a 2‐year‐old girl with CAPE who was successfully treated with ustekinumab.
ISSN:0736-8046
1525-1470
DOI:10.1111/pde.15336