Institutionalization of pharmacovigilance in a University Hospital Center: experience of the CHU Mohammed VI of Tangier in MOROCCO

Introduction: Spontaneous reporting of adverse reactions to a pharmacovigilance (PV) center is the easiest way to collect data on the safety profile of drugs. However, the Moroccan Poison Control and Pharmacovigilance Center (CAPM) cannot handle this work alone, and regional centers must be established. In this regard, a Regional PV Center (CRPV-Tangier) has been established at the University Hospital of Tangier to promote this activity in the region. Aim: Share our experience of institutionalizing pharmacovigilance in Tangier's CHU under the auspices of CRPV-Tangier as a viable model for other health structures interested in adopting such an approach. Describe the structure that will support this project and present the results of our first months of operations as a regional PV center. Materials and Methods: A narrative study on pharmacovigilance professional development at the University Hospital of Tangier covering the objectives, organization, resources, functioning, duties, and outcomes of this experience. Results and Discussion: The CRPV-Tangier is housed in the University Hospital of Tangier's pharmaco- toxicology department. CRPV-Tangier's responsibilities include: promoting PV at all CHU hospital establishments? PV should be promoted at the regional level and in collaboration with the CAPM. Human resources are represented by the Director of CRPV-Tangier, who is a pharmacologist and the head of the Pharmaco-Toxicology department at the University Hospital of Tangier; four pharmacists as correspondents (Figure 1); one referent per clinical department (approximately 35 departments); material resources; and a Pharmacovigilance Committee (14 members); operational mechanisms, such as the electronic notification circuit and the management of adverse effects with analysis; delivery of the PV database; and implementation of risk-mitigation actions in collaboration with the CAPM. The CHU services are welcoming, and the organization's results are promising.. Conclusion: The organization and structuring of the pharmacovigilance approach at CRPV-Tangier will allow this activity to be advanced and data collected in support of optimal patient care.