Clone to the rescue: a challenging case of granulomatous mycosis fungoides diagnosed by gene rearrangement studies

[...]immunohistochemical staining failed to identify an elevated CD4:CD8 ratio, and suggestive histopathological findings did not develop over time. A very high index of clinical suspicion and use of gene rearrangement studies may assist in making this challenging diagnosis. Contributors SAK, DDM an...

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Veröffentlicht in:Journal of clinical pathology 2022-04, Vol.75 (4), p.285-287
Hauptverfasser: Kullberg, Sara A, Miller, Daniel D, Boull, Christina
Format: Artikel
Sprache:eng
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Zusammenfassung:[...]immunohistochemical staining failed to identify an elevated CD4:CD8 ratio, and suggestive histopathological findings did not develop over time. A very high index of clinical suspicion and use of gene rearrangement studies may assist in making this challenging diagnosis. Contributors SAK, DDM and CB contributed to the design and implementation of the research, to the analysis of the discussion, and to the writing of the manuscript. Granulomatous mycosis fungoides and granulomatous Slack skin: a multicenter study of the cutaneous lymphoma histopathology Task force group of the European organization for research and treatment of cancer (EORTC).
ISSN:0021-9746
1472-4146
DOI:10.1136/jclinpath-2021-207658