Novel core–shell magnetic nanoparticles@Zeolitic imidazolate with glycerol‐nickel for the synthesis of dihydropyrimidinones

The present study reported a novel and eco‐friendly synthesis of Fe 3 O 4 @ZIF‐8@Glycerol‐Ni nanocatalyst via a multistep process. The as‐prepared catalyst was used due to its high efficiency, low cost, and biocompatibility for the fabrication of dihydropyrimidinones by Biginelli multicomponent reactions of aryl aldehyde, ethyl acetoacetate, and urea under ambient status. X‐ray diffraction (XRD), Fourier transform infrared spectroscopy (FT‐IR), Brunauer‐Emmet‐Teller (BET), vibrating sample magnetometry (VSM), scanning electron microscopy and energy dispersive X‐ray (SEM‐EDS), inductively coupled plasma (ICP), elemental mapping analysis (EMA), thermogravimetric analysis (TGA), Raman, and transmission electron microscopy (TEM) techniques were successfully utilized to evaluate the nanocatalyst. The advent of the peaks confirmed the presence of nickel on the catalyst's surface due to the oxygen and nickel, and the nanoparticle size is 10–15 nm. Eventually, nano‐heterogeneous catalyst exhibits high performance as well as good selectivity in the synthesis of dihydropyrimidinones. Also, it can be recycled up to multiple fresh runs with no significant loss of catalytic efficiency.