Household drug-resistant TB contact tracing in Tajikistan

Household drug-resistant TB contact tracing in Tajikistan

BACKGROUND: Tajikistan has a high burden of rifampicin-resistant TB (RR-TB), with 2,700 new cases estimated for 2021 (28/100,000 population). TB is spread among household members through close interaction and children exposed through household contact progress to disease rapidly and frequently.METHO...

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Veröffentlicht in:The international journal of tuberculosis and lung disease 2023-10, Vol.27 (10), p.748-753
Hauptverfasser: Rekart, M. L., Aung, A., Cullip, T., Mulanda, W., Mun, L., Pirmahmadzoda, B., Kliescokova, J., Achar, J., Alvarez, J. L., Sitali, N., Sinha, A.
Format: Artikel
Sprache:eng
Schlagworte:
Central Asia
Contact tracing
Drug resistance
Household Contact Tracing
Households
Original
Paediatric
rifampicin-resistant TB
Rifampin
Rr-Tb
Signs and symptoms
Skin tests
Tuberculin
Tuberculosis
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Zusammenfassung:BACKGROUND: Tajikistan has a high burden of rifampicin-resistant TB (RR-TB), with 2,700 new cases estimated for 2021 (28/100,000 population). TB is spread among household members through close interaction and children exposed through household contact progress to disease rapidly and frequently.METHODS: We retrospectively analysed programmatic data from household contact tracing in Dushanbe over 50 months. We calculated person-years of follow-up, contact tracing yield, number needed to screen (NNS) and number needed to test (NNT) to find one new case, and time to diagnosis.RESULTS: We screened 6,654 household contacts of 830 RR-TB index cases; 47 new RR-TB cases were detected, 43 in Year 1 and 4 in Years 2 or 3. Ten were aged
ISSN:1027-3719
1815-7920
DOI:10.5588/ijtld.23.0066