Electrochemical Sulphenylation/Cyclization of Quinones: A Rapid, Green, and Efficient Access to Cytotoxic Compounds

Undivided electrochemical cells enable economical preparation of sulphur‐containing naphthoquinones through electrochemical sulphenylation of quinoidal compounds. The environmentally friendly and efficient protocol eliminates the use of chemical oxidants and facilitates the synthesis of the desired...

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Veröffentlicht in:European journal of organic chemistry 2023-10, Vol.26 (38)
Hauptverfasser: Diogo, Emilay B. T., Delolo, Fábio G., Graça, Gabriela A. P., Paz, Esther R. S., Bozzi, Ícaro A. O., Diniz, Renata, Passos, Juliano P., Matencio, Tulio, Soares, Liane K., Alves, Diego, Costa, Pedro M. S., Pessoa, Claudia, Pereira, Cynthia L. M., Ackermann, Lutz, da Silva Júnior, Eufrânio N.
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Sprache:eng
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Zusammenfassung:Undivided electrochemical cells enable economical preparation of sulphur‐containing naphthoquinones through electrochemical sulphenylation of quinoidal compounds. The environmentally friendly and efficient protocol eliminates the use of chemical oxidants and facilitates the synthesis of the desired molecules. This approach offers an efficient and versatile method to synthesize quinones that exhibit cytotoxicity against cancer cell lines.
ISSN:1434-193X
1099-0690
DOI:10.1002/ejoc.202300506