Pre-Emptive Analgesia by Intraperitoneal Instillation of Lignocaine in Laparoscopic Cholecystectomy

Objective: To compare the effects of preemptive intraperitoneal instillation of local anesthetic (lignocaine) with conventional instillation after the removal of gall bladder in elective laparoscopic cholecystectomy. Study Design: Quasi-experimental study. Place and Duration of study: General Surgical ward, Combined Military Hospital, Rawalpindi Pakistan, from Jan to Apr 2018. Methodology: Patients fulfilling the inclusion criteria were randomly assorted into two groups. Group A received intraperitoneal lignocaine at the conventional timing where was in Group B local anesthetic was instilled preemptively at the time of insertion of trocar. Post operatively pain was measure on visual analogue scale at 3,6 and 12 hours. Results: Total of 184 patients were followed up post-operatively. Mean age of patients in Group A was 44.5±13.57 years and in Group B was 46.2±13.9 years. Mean post-operative pain on visual analogue scale score for Group A was 2.53±0.73 and that for Group B was 2.0±0.66 with p-value