Visit-to-visit ultrafiltration volume variability predicts all-cause mortality in patients receiving hemodialysis

Little is known about the effect of visit-to-visit ultrafiltration volume (UV) variability on the outcome. In this study, we investigated the association between visit-to-visit UV variability and all-cause mortality in patients receiving hemodialysis (HD). We consecutively enrolled patients who rece...

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Veröffentlicht in:Renal failure 2023-12, Vol.45 (1), p.2194439-2194439
Hauptverfasser: Zhang, Quanchao, Wang, Ning, Nie, Ling, Lu, Caibao, Chen, Hongwei, He, Wenchang, Li, Moqi, Wang, Yiqin, Zhao, Jinghong, Xiong, Jiachuan
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Sprache:eng
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Zusammenfassung:Little is known about the effect of visit-to-visit ultrafiltration volume (UV) variability on the outcome. In this study, we investigated the association between visit-to-visit UV variability and all-cause mortality in patients receiving hemodialysis (HD). We consecutively enrolled patients who received maintenance HD in our center from March 2015 to March 2021. UV variability was defined using standard deviation (UVSD) and coefficient of variation (UVCV) (standard deviation divided by the mean). The relationship between UV variability and all-cause mortality was assessed using univariate and multivariate Cox proportional hazard regression models. Receiver operating characteristic curves were used to evaluate the predictive abilities of UVSD and UVCV for short-term and long-term survival rates. A total of 283 HD patients were included. The mean age was 57.54 years, and 53% were males. Follow-up was done for a median of 3.38 years (IQR 1.83-4.78). During the follow-up period, 73 patients died. Cox proportional hazards models indicated that UVSD and UVCV (higher versus lower) were positively associated with all-cause mortality (p=.003 and p
ISSN:0886-022X
1525-6049
DOI:10.1080/0886022X.2023.2194439